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Glossary
Magnetic Resonance Imaging (MRI)

Traditional axial image from a 3T MRI system.
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Magnetic resonance imaging (MRI) is the
newest, and perhaps most versatile, medical imaging technology available.
Doctors can get highly refined images of the body's interior without
surgery, using MRI. By using strong magnets and pulses of radio waves to
manipulate the natural magnetic properties in the body, this technique makes
better images of organs and soft tissues than those of other scanning
technologies. MRI is particularly useful for imaging the brain and spine, as
well as the soft tissues of joints and the interior structure of bones. The
entire body is visible to the technique, which poses few known health risks.
More from this article
here. |
Diffusion Tensor Imaging MR-DTI

DTI measures the diffusion of water molecules in biological tissues. Axial
slice. |
Diffusion Tensor Imaging is a building block
of the fiber-tracking images. The images are presented as a set of slices,
in some ways similar to traditional MRI. But in DTI, the information is
presented in colors that represent the predominant direction of movement, or
diffusion, of hydrogen atoms within water molecules.
Though water appears move around freely, individual
water molecules are constantly in motion, colliding with each other and
encountering other cellular structures from time to time at high speeds.
These high-speed collisions cause the water molecules to diffuse. In this
case diffusion causes a drop of a dye which is placed at the center of a
beaker of water to slowly spread apart in a spherical pattern. Water in
tissues containing a large number of fibers such as skeletal muscle, and
brain white matter diffuse fastest along the direction that the fibers are
pointing in, and slowest at right angles to it. DT-MRI renders all the
complex information about how water diffuses in tissues into intricate
three-dimensional representational maps of the tissues.
Such data can, for example, be used to visualize and
study the connectivity and continuity of neural pathways in the central and
peripheral nervous systems.
Diffusion Tensor Imaging (DTI) is becoming a routine
magnetic resonance technique to study white matter properties and
alterations of fiber integrity due to pathology. |
Fiber Tracking Image from MR-DTI

Colors code the direction of fiber travel: red is side to side, blue is up
and down, and green is front to back. |
Fiber tracking images are the result of data processing
algorithms that are applied to DTI data. Data points with comparable
characteristics are linked to one another. The resulting information is
presented as 3-D bands, strings, or tubes that use color to reinforce the
information about direction.
MRI Fiber Tracking (MR-FT) images are being
used to evaluate patients with white matter disease such as multiple
sclerosis.
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